” This can appear in multiple apps, from Skype to HP 3D DriveGuard (accelerometerst.exe). When trying to launch an application, you may get the error message “ The program can’t start because VCRUNTIME140.dll is missing from your computer. This is a common issue with Windows 10, and it can be quite frustrating. Try reinstalling it to fix this problem.'? Have you ever tried to open an app on your computer only to see the error 'The program can't start because vcruntime140.dll is missing from your computer.